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So, the metabolite is to blame for about 20% of sildenafil's motion. Sildenafil is excreted as metabolites predominantly inside the feces (about eighty% of administered oral dose) and to a lesser extent from the urine (close to thirteen% from the administered oral dose). If taken that has a high-Extra fat meal, absorption is minimized; the time taken to reach the most plasma concentration raises by all around a person hour, and the maximum concentration by itself is lessened by practically a single-third.[fifty two]
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